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The experimental ophthalmology section is a centre with the principal objective of optimising the treatment of retinal diseases. Our interest is the promotion of regenerative and personalized medicine such as the development of cell-based, GMP compliant Advanced Therapy Medicinal Products (ATMP) to treat neurodegeneration.
The clinical and glaucoma research of our department comprises the transfer of therapeutic approaches developed in our laboratories into the clinic and clinical trials for new drugs and innovative surgical procedures, especially focusing on the optimisation of treatment approaches for glaucoma.
We are working on the psychophycial aspects related to prosthetic vision and collaborate with the company Second Sight Medical Products Inc. for the clinical testing of their retinal implant Argus II®.
GMP-grade production and transplantation of cell-based gene therapeutic products from autologous biopsies for personalized medicinal approaches developed in our department. Iris pigment epithelial cells are harvested by an iridectomy (1) and transported to the GMP-facility where they are isolated and separated (2). Next, the cells, resuspended in a special buffer, are electroporated and the therapeutic gene is integrated into the cells’ genome (3). The genetically modified cells are transplanted subretinally (4) in the same patient within one single surgical session of approximately 60 min.
Head of division
Prof. Gabriele Thumann, firstname.lastname@example.org
Experimental and translational ophthalmology
PD Dr. Andreas Weinberger, email@example.com
Dr. Argyrios Chronopoulos, firstname.lastname@example.org
Dr. Mateusz Kecik, email@example.com
Dr. Mohamed Asrih, firstname.lastname@example.org
Dr. Tereza Bautzová, email@example.com
Dr. Nina Harmening, firstname.lastname@example.org
Dr. Martina Kropp, email@example.com
Dr. Cécile Prat-Souteyrand, firstname.lastname@example.org
Alain Conti, email@example.com
Gregg Sealy, firstname.lastname@example.org
Retinal implant and visual psychophysics